Bone Grafts and Substitutes Market - by Product (Allografts {Machined Allografts and Demineralized Bone Matrix}, Bone Graft Substitutes {Morphogenic Proteins (BMP) and Synthetic Bone Grafts}, and Cell-Based Matrices), by Applications (Spinal Fusion, Trauma, Craniomaxillofacial, Joint Reconstruction, and Dental Bone Grafting), by End User (Hospitals & Clinics, Home Settings & Ambulatory Surgical Centers, and Others), and By Region- Global Opportunity Analysis and Industry Forecast, 2020 - 2030

Market Overview:

Bone Grafts and substitutes market accounted USD 2,826 million in 2020 and is expected to reach USD 4967 million by 2030, at a CAGR of around 5.8%. Bone grafts and substitutes are implantable materials which support bone formation, bone healing, and osseous reconstruction. These materials are significantly used to treat bone defects. The fundamental properties of bone graft are structural support, osteogenesis, osteoconduction, and osteoinduction. They are used in sports, trauma plastic, facial, and spinal surgery. Moreover, they can be used to fill cavities in case of lack of bones or help in the provision of structural stability. It is an operating procedure for replacing a missing or defected bone with a material (bone graft) from a patient’s own body, corpse, animals, or a different person. It finds its application in wound healing, complex fracture treatment, and others. Bone grafts are used in surgical procedures such as bone replacement, spinal fusion surgeries, ensuring new bone formation, and repair of bone fractures. Moreover, they are applicable in the treatment of various bone-related disorders such as congenital pseudoarthrosis, dental bone grafting problems, and complex fractures.

Market Segmentation:

The global bone grafts and substitutes market is divided based on the product, application, and region. Based on the product, the market is categorized into bone graft substitutes, allografts, and cell-based matrices. The allografts are further divided into demineralized bone matrix and machined allografts. The bone graft substitutes section is further categorized into bone morphogenic proteins (BMP) and synthetic bone grafts. Based on applications the market is characterized into spinal fusion, trauma, craniomaxillofacial, joint reconstruction, and dental bone grafting. Based on the end-user, the market is classified into hospitals & clinics, home settings & ambulatory surgical centers, and others. Owing to the rising demand for pesticides and fertilizers to induce higher crop production in the region. Geographic breakdown and analysis of each of the aforesaid segments includes regions comprising North America, Europe, Asia-Pacific, and RoW.

Market Dynamics and Factors:

According to the CDC report, around 32% of the adult population and 60% of the elderly population affected by spinal deformities as of 2017. For instance, 488,000 spinal procedures performed in the U.S. The common cause of spinal fusion injury found to be trauma, falls, collision or road traffic accidents which are estimated to propel the growth of the market. Moreover, development of biocompatible synthetic bone grafts, rise in incidence of musculoskeletal disorders, technological advancements in the medical field leading to a shift from autograft to allograft is driving the growth of the market. Additionally, according to the American Dental Association report, around 95% to 98% success rate has been reported for dental implant surgeries as of 2017. Every year in the U.S. about 5 million implant procedures are performed. However, ethical issues and the high cost of surgeries related to bone grafting procedures restrict the market growth. Conversely, growth prospects in the emerging markets, rise in interests of key players toward R&D activities in bone grafts & its substitutes, and increase in demand for orthopaedic procedures mainly in geriatric population are anticipated to provide beneficial opportunities for growth of the market in near future. According to the CDC, the worldwide incidence of hip fracture is expected to increase by over 240% in women and over 310% in men by 2050. Which stands as a gateway of opportunities. Moreover, the rate of grafting is increasing due to an increased incidence of bone fractures. In addition to that, the demand for the market is further increased due to the increase in adoption of minimally invasive surgeries (MIS).

Geographic Analysis:

Region-wise, North America is expected to lead the global bone grafts and substitutes market in upcoming years. In 2018, about 37% of the market share was held by North America. The U.S., in particular, is leading the global market by creating huge product demand, owing to a high prevalence of trauma-related injuries and orthopaedic diseases. According to the International Osteoporosis Foundation, in the U.S., 44 million men and women above the age of 50 have osteoporosis or low bone mass, which symbolizes 55% of Americans in that age group which is also driving the North American market. In 2018, Europe was the second prominent market globally, owing to the rising demand for innovative and technologically advanced therapies for chronic diseases treatment coupled with the presence of leading market players, such as Orthofix Holdings, Stryker, and ohers. Also, the developed healthcare infrastructure in Germany, Russia, France, and the UK is expected to drive this regional market. Europe is anticipated to show fast growth in the market globally in the years ahead. The Asia Pacific is predicted to show the highest growth rate in the market in the future globally. Developing healthcare infrastructure coupled with the rising prevalence of spinal disorders is driving the Asia Pacific bone grafts and substitutes market. Likewise, the growth can be attributed to increased medical tourism offering advanced healthcare services at affordable costs and growing awareness among the regional population about bone grafts and substitutes will auxiliary boost this regional market over the projected period. Developing countries like China and India are projected to contribute major shares in terms of revenue to the regional market. On the contrary, stringent regulatory guidelines limit the adoption in some of the countries. In South Korea, the product should be approved by the Korean Food and Drug Administration (KFDA) before marketing. The stringent regulatory scenario in Japan limits the entry of foreign players in the country. However, with the recent approval of DBM in Japan in 2019, the allograft market is dignified to register beneficial growth in this region over the coming few years.

Competitive Scenario:

The major players operating in this market include Medtronic Plc, Stryker Corporation, DePuy Synthes, Integra Lifesciences Holdings Corporation, Wright Medical Group N.V., Zimmer Biomet Holdings, Inc., Xtant Medical Holdings, Inc., (Bacterin), Arthrex, Inc., Baxter International Inc., and Musculoskeletal Transplant Foundation (MTF).

Bone Grafts and Substitutes Market Report Scope